Endocrine Abstracts

Method: We carried out a retrospective audit of baseline data for patients under our care with primary hyperparathyroidism on cinacalcet therapy, against the NHS England Clinical Commissioning Policy (July 2016). Patients with secondary hypercalcaemia due to end stage renal failure were excluded.Results: 40 patients were identified, 9 men and 31 women, with an age range of 32–89 years (median age 78). 3 patients were under 50 ...

Introduction: Diabetic Ketoacidosis (DKA) is a potentially life threatening complication of type-1 diabetes mellitus (T1DM) in children and young people (CYP). An Integrated Care Pathway (ICP) for management of DKA is based on the current British Society for Paediatric Endocrinology and Diabetes (BSPED) guidelines. The BSPED guideline moved away from cautious fluid replacement toward a liberal approach for resuscitation and maintenance fluids based on current evidence. The ICP...

Keywords: COVID-19, Diabetes Mellitus, PaediatricsIntroduction: COVID-19 has a complex relationship with diabetes. There is anecdotal evidence that it could be causative for new onset diabetes in paediatrics. In this audit, we aim to study our cohort of new onset diabetes in children and young people (CYP) during the COVID pandemic in a DGH setting. We sought to identify any causative or associational link between COVID-19 and new onset diabetes.<p c...

Background and Aims: The objective of our study is to evaluate the degenerative profile in diabetic patients and their glycemic controlMaterials and Methods: This analytical cross-sectional study for analytical purposes was conducted during the period from January 2022 to January 2023, within the department of endocrinology and metabolic diseases of the Military Hospital of Instruction Mohamed V of Rabat.Results: 215 patients were ...

Background: The incidental adrenal lesion, coined ‘incidentaloma’, is a common radiological finding, necessary of further investigation and diagnosisAims: This is a retrospective observational study which aims to identify the prevalence of incidentaloma in CT scans of the abdomen and pelvis in the Brighton & Sussex University Hospital’s Trust. Our additional objective is to assess the adequacy of incidentaloma management throu...

A 39 years old lady who started to develop hypoglycemia three month following gastric bypass surgery. She is known to have Type 2 DM, dyslipidemia hypertension and Hirsutism. Her weight on presentation was 93.5 kg (pre operation was 104 kg) and Ha1c was 6% (pre operation was 10.5%). She was off diabetes medications. Hypoglycemia mainly fasting some readings < 3 mmol/l, with symptoms (diaphoresis, fatigue and weakness) but sometime hypoglycemia occur 2–3 h post prandia...

Introduction: Although a number of studies have reported on the External Masculinisation Score (EMS) and have validated its use for numerical descriptions of the external genitalia, the methodology in these studies has not considered longitudinal changes in EMS.Objectives: To examine longitudinal changes in EMS in boys with XY Disorders of Sex Development (DSD) and determine the causes of these changes.Methods: All boys of confirme...

Case history: A 44 year old black African woman was referred to the endocrinology clinic for investigation of abnormal thyroid function tests. She had initially presented with palpitations and sweats. She had no significant past medical history and was not taking any prescribed medications or over the counter preparations. On examination, she was clinically euthyroid and did not have any abnormal findings of note.Investigations: Biochemical investigation...

Introduction: Hypogonadism is linked to anaemia, sarcopenia and osteoporosis in men. Whereas secondary hypogonadism (SH) is biochemically indistinguishable from nongonadal illness, primary hypogonadism (PH) can be easily diagnosable by the identification of raised gonadotropins.Case Presentation: A 66-years old male with a background history of type 2 diabetes mellitus, arthritis, and hypertension was referred to the haematology services to investigate h...

Background: Hyponatraemia is a frequent finding in medical inpatients, where a comprehensive evaluation is warranted to establish the underlying mechanism and guide further management. Whilst the role of confounding medications, syndrome of inappropriate anti-diuretic hormone (SIADH), adrenal insufficiency and polydipsia is well-established as causative factors in the development of hyponatremia, the link between hypothyroidism and hyponatremia is controversial in the medical ...